Berberine is a natural plant alkaloid found in goldenseal, barberry, goldthread, and Oregon grape. This well-tolerated extract works at the cellular level to support normal responses, even after eating a meal or sweet treat. In vitro evidence suggests Berberine works by helping to enhance AMPK-activated protein kinase, which controls the synthesis and uptake of glucose transporters that move glucose from your bloodstream into your cells. One study showed that 1,500 mg of Berberine daily supports normal responses after meals along with 3-month averages. Doctors’ Preferred Berberine is backed by Triple-Testing Philosophy, which includes rigorous screening of raw materials, finished goods batch testing, and independent third-party lab testing. The result is a stellar 30-year reputation for outstanding quality and safety.

Doctor's Suggested Use: Take 3 capsules daily—1 before each meal.

Serving Size: 1 Capsule

Servings Per Container: 90

Ingredient: Berberine Hydrochloride (BerberPure™) 500 mg

Other ingredients: Microcrystalline cellulose, gelatin, magnesium stearate, gum acacia, silica

Precautions: Consult a health care practitioner before use if you are on insulin or are hypoglycemic, are pregnant or nursing, have a serious medical condition, or use any other medications.

Keep out of reach of children.

Gluten Free

BerberPure™‡ is a trademark of Healthy Directions.

Science and Quality

Where does this amazing phytonutrient come from?

Berberine is a plant alkaloid, a naturally occurring chemical compound found in herbs such as goldenseal, Oregon grape, barberry, and goldthread. While you may be able to find berberine in a few supplements here and there, it’s rare and unlikely you’ll find the dose that helps maintain normal blood sugar levels—which means a lot of folks are missing out on the most powerful benefits.

That changes with Clinical Grade Berberine supplement formula, as it gives you the full research dose of 1,500 mg, shown to help support blood sugar, cholesterol, and triglyceride levels already in the normal range.

Berberine Supports Healthy Blood Sugar and More!

In one part of a two part study, individuals were given three 500 mg doses of berberine daily (the same dose in Clinical Grade Berberine for three months. Research showed that berberine supports a healthy blood glucose response to a meal. In the second part of this study, individuals were also given three 500 mg doses of berberine daily and the trial showed that berberine helps maintain blood sugar levels already in the normal range, supports a healthy blood lipid profile, and supports healthy total and LDL cholesterol levels.1

1Zhao W, et al. Biomed Pharmacother 2008;62(10):730–1.

Product Quality

In addition, Berberine is manufactured under stringent quality controls:

• Manufactured to exacting standards using highest quality raw materials

• Produced in accordance with our strict Standard Operating Procedures (SOPs) that meet those set by the FDA’s Good Manufacturing Practices

• Every batch tested to verify purity and potency specifications are met

• Quality assured with our Triple-Testing Philosophy™

• Backed by our 100% satisfaction guarantee